Valacyclovir renal toxicity

Cold Sores (Herpes Labialis): Valacyclovir tablets, USP are indicated for treatment In the event of acute renal failure and anuria, the patient may benefit from. Valtrex is indicated for the treatment of herpes zoster (shingles) and Renal impairment, acute renal failure (especially in elderly patients or in. Asahi et al (7) reviewed 20 cases of chronic renal failiue, and both of the other 3 cases, without previous renal failure, had acute renal failure.

Intravenous acyclovir generates higher peak levels than oral valacyclovir. Although this feature may confer more potent activity, it may also increase the risk of renal toxicity due to precipitation of acyclovir crystals in the renal tubules [3] (see "Crystal-induced acute kidney injury (acute renal failure)"). Valacyclovir is generally well tolerated, but serious adverse drug reactions have been reported including neurotoxicity and acute renal failure, especially in the.

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